Jedi Knight/Sith Warrior
Jedi Consular/Sith Inquisitor
This is my general UI layout I have been using for quite a few years in other games. It is designed with a mouse with a minimum of two side buttons which are mapped to the two sidebars in 4x3. It is a very flexible layout and works great for me in healing, tanking and DPS situations. It is also spaced so you can use two chat windows on each side of the UI so you can separate the usually constant stream of chat in general from guild or group messages in the other chat window.